The skin around the eyes ages differently and faster if left untreated. It exhibits significant anatomical and dermatological differences compared to other areas of the face. These differences directly impact the aging behavior of this zone, which becomes clinically visible through the early appearance of wrinkles, loss of elasticity, and volume loss. The aging processes around the eyes are influenced internally by genetics and hormonal status, and externally by UV exposure and environmental factors.
The skin around the eyes is on average only about 0.33 mm thick and six times thinner than the skin on the cheek, which is about 2 mm thick. This is due to a thinner outer layer of skin (epidermis) and an almost non-existent layer of fat beneath the skin, the subcutis, which makes the skin particularly sensitive to external stimuli.
The skin around the eyes contains less sebum and fewer sweat glands. As a result, the skin is less hydrated and dries out more easily, which further promotes the formation of wrinkles.
UV radiation leads to the formation of free oxygen radicals, which is particularly effective in the area around the eyes. Oxidative stress and the associated inflammatory processes, via the factors interleukin-6 and TNF-α, lead to the accelerated degradation of the extracellular matrix.
The extracellular matrix (ECM) is the essential supporting and networking framework surrounding skin cells. Produced by connective tissue cells (fibroblasts), it determines the structure and function of the skin tissue around the eyes. It consists of collagen fibers (providing firmness), elastin (ensuring elasticity), hyaluronic acid (binding moisture), proteoglycans, and glycoproteins (mediating between cells and fibers). The ECM thus forms the "foundation" in the middle layer of the skin, which is the primary component of the skin around the eyes. It ensures that the skin remains elastic, plump, and resilient. Beginning in young adulthood, the ECM is broken down or damaged, which can lead to wrinkles, loss of elasticity, and dryness at an early age. Furthermore, the underlying subcutaneous fat and bony structure diminish over time, which can result in under-eye bags, shadows, and a sunken appearance around the eyes.
Over time, fibroblasts, the important connective tissue cells of the skin, enter a state of cellular aging (senescence) due to damage such as DNA alterations, shortened chromosome ends (telomeres), or free oxygen radicals, which the cells themselves also produce. These cells, colloquially referred to as "cell zombies" in scientific terms, no longer divide or renew themselves, but they remain active and secrete pro-inflammatory messenger substances.
Recent cell research shows that this so-called SASP (senescence-associated secretory phenotype) has a negative effect on surrounding cells. Its interaction with fat stem cells in the skin leads to chronic inflammation, collagen breakdown, and accelerated skin aging, particularly visible in the thin and sensitive periorbital skin around the eyes. It is essential to intervene in this disrupted cell communication and halt the aging process.
The periorbital eye area differs in that it has thinner skin, lower fat reserves, and fewer sebaceous glands. Therefore, it is particularly susceptible to early and visible signs of aging. Active ingredients for the periorbital eye area must thus be specifically formulated and dosed to address the anatomical and dermatological characteristics of this region. Furthermore, a base that does not migrate into the eyes is essential. The lipid-rich formula with fast-absorbing carriers helps to avoid over-treating or irritating the sensitive skin.