Science Hub
Our Commitment
We are all getting older, living more consciously and actively: working, traveling, exercising, maintaining routines, and always online. Your skin often shows the effects of this stress first. Medical science sees it as a reflection of your healthspan and even your lifespan. Inspired by the WHO's Decade of Healthy Ageing initiative, we develop formulations based on the principles of Preventive Longevity, clinically sound and dermatologically tested, to support skin health and well-being in the long term.
Our active ingredient lexicon
AHA complex
Allantoin
Almond Oil
Aloe Vera
Ameliox™
Amino acid complex
Arginine
Argireline
Ascorbyl Palmitate
Azelaic acid
Betapur™
Bio-Placenta Complex
Biophytex™
Biotechnological ferments
Bisabolol
Boswellia extract
Butylene Glycol + Propanediol
Celligent
Centella complex
Coenzyme Q10
Dragon's Blood
Ectoine
Evermat™
Folic Acid
Galactoarabinan
Glycerin
Glycine Soja Oil
Witch hazel extract
Jojoba oil
Chamomile flower extract
Kigelia Africana Fruit Extract
Lipochroman™
Liposome
almond oil
Matrixyl™ 3000
Matrixyl OS 3000
Melostem™
Lactic acid
Neurolight™
Niacinamide
Oligohyaluron
Panthenol
PDRN
Pentavitin
Saccharide Isomerated
Pullulan
Renovage™
Resveratrol
Retinatural™
Salicylic Acid
Sheabutter
Sodium Lactate
Sodium PCA / PCA
Sunflower oil
Syn®-Ake
Tranexamic acid
Grape seed oil
Unisooth™
Vitamin A palmitate
Vitamin E
Wild Yam Extract
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Triple hyaluronic acid complex
This complex combines three molecular weights of hyaluronic acid:
Hydrolyzed Hyaluronic Acid (ultra-low molecular weight) for deeper penetration,
Hydrolyzed sodium hyaluronate (low molecular weight) for middle layers and
Sodium Hyaluronate (high molecular weight) for surface moisture retention.
This synergistic combination offers both immediate and long-lasting hydration, reduces transepidermal water loss (TEWL), and promotes skin smoothness and elasticity. Studies on the branded ingredient Hyacare® 50 demonstrate proven anti-wrinkle effects and barrier improvement – making it particularly suitable for dehydrated, mature, or stressed skin.
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AHA complex
Glycolic and lactic acids are alpha hydroxy acids (AHAs) used in skincare for their exfoliating and moisturizing properties. Glycolic acid (from sugar cane) has the smallest molecular weight and penetrates particularly deeply, while lactic acid also provides hydration.
Both AHAs break down the intercellular bonds of dead skin cells, promote desquamation, and stimulate epidermal cell division. Simultaneously, they improve moisture retention, stimulate collagen production, and result in smoother, more radiant skin. The AHA complex is particularly effective for dull skin, uneven skin tone, acne scars, and the first signs of wrinkles.
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Allantoin
Allantoin is a uric acid derivative, either synthetically produced or derived from comfrey (Symphytum officinale), with wound-healing and skin-soothing properties. It promotes cell proliferation and the differentiation of keratinocytes, thus supporting skin renewal.
Allantoin has soothing, keratolytic, and antioxidant properties. It helps to remove dead skin cells without irritating the skin, thereby improving its smoothness and absorption capacity for other active ingredients. Due to its excellent tolerability, it is used in numerous skincare products for sensitive, irritated, dry, or stressed skin.
Almond Oil
Almond oil is obtained by cold pressing the kernels of the sweet almond (Prunus amygdalus dulcis) and consists primarily of monounsaturated fatty acids such as oleic acid, as well as polyunsaturated linoleic acids. It is rich in natural lipids, vitamin E, and secondary plant compounds that have antioxidant and skin-soothing properties.
The lipid components of almond oil specifically support the restoration of the skin barrier and reduce transepidermal water loss (TEWL). At the same time, it improves skin elasticity and, thanks to its mild anti-inflammatory properties, soothes irritations and dryness. Due to its excellent tolerability, almond oil is widely used for sensitive, atopic, or mature skin.
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Aloe Vera
Aloe vera gel is obtained from the leaf pulp of the Aloe barbadensis plant and consists of approximately 99% water as well as over 75 active substances, including polysaccharides (especially acemannan), amino acids, vitamins, enzymes and minerals.
The polysaccharides bind moisture and form a protective film on the skin. At the same time, they have an anti-inflammatory effect and support wound healing by stimulating fibroblast activity and collagen synthesis. Aloe vera exhibits antioxidant and antimicrobial properties, improves skin elasticity, and reduces irritation. This active ingredient is frequently used for sun-stressed, irritated, or dehydrated skin.
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Ameliox™
Silymarin is a flavonolignan complex extracted from the seeds of milk thistle (Silybum marianum). The main active ingredient complex comprises silibinin, silychristin, and silydianin. These substances have strong antioxidant, anti-inflammatory, and cell-protective properties.
In skincare, silymarin protects keratinocytes and fibroblasts from UV-induced oxidative stress, inhibits lipid peroxidation, and reduces inflammatory processes, for example, by inhibiting NF-κB activation. Silymarin has been shown to slow skin aging, reduce pigmentation irregularities, and strengthen the skin barrier function. Branded raw materials such as Silymann® offer standardized extracts with proven bioactive effects.
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Amino acid complex
The complex consists of 12 proteinogenic amino acids and acetylglutamine, which function as essential components of the skin's natural moisturizing factor (NMF). They are biocompatible and play a key role in cell metabolism, protein biosynthesis, and the skin's barrier and repair functions.
These amino acids promote hydration, improve skin elasticity, protect against transepidermal water loss, and help restore impaired skin functions. Arginine also promotes wound healing, while glycine and serine have soothing properties. The complex is particularly suitable for dry, sensitive, or stressed skin.
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Arginine
Arginine is a basic, proteinogenic α-amino acid and a natural component of the skin's own Natural Moisturizing Factor (NMF). In cosmetic formulations, it is used as a moisturizing agent and pH buffer. Arginine can also improve skin microcirculation via nitric oxide (NO)-dependent mechanisms.
At the cellular level, arginine promotes regeneration and supports skin repair processes through its role in cell metabolism (e.g., as a substrate for fibroblast proliferation). It also exhibits protective properties against skin stress and has a mild anti-inflammatory effect. Arginine is frequently used in combination with other amino acids or moisturizing factors in skincare products to stabilize the skin barrier and improve skin elasticity.
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Argireline
Argireline® is a synthetic peptide (Acetyl Hexapeptide-8) developed as a neurotransmitter inhibitor. It mimics the SNAP-25 fragment of a SNARE complex, which plays a role in the release of acetylcholine, thereby reducing muscle contraction.
In the skin, this leads to a temporary reduction of expression lines. Clinical studies show that Argireline produces visible effects on the forehead and around the eyes after just a few weeks. It is considered a well-tolerated alternative or complement to injectable neurotoxins and is frequently used in anti-wrinkle serums.
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Ascorbyl Palmitate
Ascorbyl palmitate is a fat-soluble ester of ascorbic acid (vitamin C) and palmitic acid. This form is more oxidation-stable than pure vitamin C and is well-suited for oil-based formulations.
In the skin, ascorbyl palmitate acts as an antioxidant, inhibits tyrosinase (→ brightening effect in hyperpigmentation), and promotes collagen production. Due to its lipophilic nature, it can penetrate the skin more easily and be converted there into active vitamin C. It is particularly suitable for mature, sun-damaged, or unevenly pigmented skin.
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Azelaic acid
Azelaic acid is a naturally occurring dicarboxylic acid found in grains such as wheat and barley. In dermatology, it is primarily used to treat acne, rosacea, and hyperpigmentation. Its effects are multifactorial: azelaic acid inhibits bacterial proliferation (e.g., Cutibacterium acnes), has comedolytic properties, and reduces the activity of 5-α-reductase, thus influencing sebum production.
At the cellular level, azelaic acid inhibits the mitochondrial enzyme function of abnormal melanocytes, thereby regulating pigmentation (antimelanocytic). It also exhibits antioxidant activity by reducing free radicals. Its use in concentrations between 10 and 20% has been clinically proven in the treatment of inflammatory skin diseases and post-inflammatory hyperpigmentation.
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Betapur™
Betapur™ is a patented branded raw material based on Salix alba extract (white willow bark), enriched with natural salicylate precursors. It belongs to the group of plant-based BHA alternatives and has skin-clarifying, sebum-regulating, and pore-refining effects.
The secondary plant compounds it contains, especially salicin, have a mild keratolytic and anti-inflammatory effect. Betapur regulates sebum production and inhibits pro-inflammatory processes via COX-2 and NF-κB. Unlike synthetic salicylic acid, this active ingredient is particularly well-tolerated by the skin and is therefore suitable for blemished, sensitive, or oily skin. It is often used in medically inspired cleansers or clarifying serums.
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Bio-Placenta Complex
This biomimetic active ingredient complex contains several synthetically produced signal peptides that are modeled on natural growth factors.
Oligopeptide-1 (EGF-like) promotes cell proliferation,
Oligopeptide-2 has an immunomodulatory effect,
Oligopeptide-3 supports cell adhesion,
Hexapeptide-11 stimulates collagen and elastin synthesis.
Together, they improve epidermal regeneration, strengthen the dermal structure, and counteract age-related degradation of the extracellular matrix. The complex is ideal for mature, dull, or atrophic skin and can also be used to support post-aesthetic treatments.
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Biophytex™
Biophytex™ is a synergistically formulated complex of plant extracts, moisturizing and vascular-active components.
Escin (horse chestnut), Ruscus extract (butcher's broom) and glycyrrhizic acid (licorice) have anti-inflammatory, vascular sealing and decongestant effects.
Centella asiatica and calendula support microcirculation and regeneration.
Hydrolyzed yeast protein has an immunomodulatory effect, while panthenol and glycerin nourish and hydrate.
This combination reduces redness and vascular reactions (e.g., in cases of couperose, rosacea, or stress), protects capillaries, and soothes irritated skin. Clinically tested and well-tolerated.
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Biotechnological ferments
The combination of Bacillus/Soybean Ferment Extract and Lactobacillus Ferment is based on biotechnological processes (fermentation of soybeans and lactic acid bacteria). This process produces bioactive metabolites such as enzymes, peptides, amino acids, and postbiotic substances.
These enzymes strengthen the skin barrier, have antimicrobial properties, and promote a balanced microbiome. They also increase moisture retention, boost enzyme activity in the skin, and soothe irritations. Areas of application include stressed, sensitive, or barrier-impaired skin conditions, as well as microbiome-friendly skincare regimens.
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Bisabolol
Bisabolol is a naturally occurring, monocyclic sesquiterpene alcohol derived from chamomile (Matricaria recutita) or of synthetic origin. The biologically active form is α-bisabolol.
It has anti-inflammatory, antimicrobial, and antioxidant properties. At the cellular level, bisabolol inhibits prostaglandin synthesis and reduces the activity of pro-inflammatory mediators. It accelerates wound healing, relieves itching, and stabilizes the skin barrier. Due to its high tolerability, it is an ingredient in many skincare products for sensitive, irritated, or reactive skin.
Boswellia extract
The extract from the resin of the Indian frankincense tree (Boswellia serrata) contains boswellic acids, which have a strong anti-inflammatory effect by inhibiting 5-lipoxygenase and NF-κB – key mediators in skin inflammation.
In cosmetics, boswellia extract is used for sensitive, stressed, or aging skin. It reduces redness, has an antioxidant effect, and can soothe the skin without suppressing the immune system. The active ingredient is particularly suitable for the care of skin with atopic dermatitis, rosacea, or photoaging.
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Butylene Glycol + Propanediol
Butylene glycol and propanediol are dihydric alcohols (glycols) used in cosmetic formulations as humectants, solvents, and penetration enhancers. They bind water in the skin and improve the texture and spreadability of products.
Both substances increase the bioavailability of lipophilic active ingredients and help stabilize the skin barrier function. Propanediol is also considered a skin-friendly, plant-based alternative to propylene glycol and has a favorable irritation profile. The combination is suitable for all skin types, including sensitive skin.
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Celligent
Celligent protects skin cells from UV and blue light-induced damage, supports DNA repair and prevents light-induced skin aging.
Centella complex
This complex contains the main bioactive components from Centella asiatica (tiger grass), a traditional medicinal plant extract from Ayurvedic and Chinese medicine.
Asiaticoside promotes collagen synthesis,
Madecassic acid has antioxidant and regenerative properties.
Asiatic acid strengthens the extracellular matrix.
Together, they have anti-inflammatory, wound-healing, and antioxidant effects. The Centella complex is used in modern dermatology to treat sensitive, irritated, or damaged skin, including post-inflammatory hyperpigmentation or after dermatological procedures.
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Coenzyme Q10
Ubiquinone (coenzyme Q10) is a naturally occurring, fat-soluble molecule that acts as a cofactor in cellular respiration within the mitochondria. In skincare, it primarily serves as an antioxidant, neutralizing free radicals and improving the energy supply to skin cells.
Q10 protects lipid membranes from oxidation, stabilizes cell structures, and reduces UV-induced skin aging. In vitro and clinical studies show that regular use can lead to improved skin elasticity and a smoothing of fine lines. Especially suitable for mature, stressed, and sun-exposed skin.
Dragon's Blood
The deep red resin extract of the South American Croton Lechleri tree is rich in proanthocyanidins, taspins and lignans, which have strong anti-inflammatory, antioxidant and wound-healing effects.
In skincare, "dragon's blood" is used to regenerate damaged skin, treat microlesions, and strengthen the skin's barrier function. It protects against oxidative stress, inhibits the release of inflammatory cytokines, and stimulates re-epithelialization. It is particularly suitable for sensitive, irritated, or stressed skin, as well as in post-interventional skincare products.
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Ectoine
Ectoin is a cyclic amino acid derivative produced by halophilic microorganisms under extreme conditions (heat, UV radiation, salt). In skincare, it acts as a cell-protective, anti-inflammatory, and membrane-stabilizing molecule.
Ectoin stabilizes proteins, cell membranes, and DNA, protects against oxidative and osmotic stress, and reduces the release of pro-inflammatory cytokines. It improves skin hydration, supports the skin's barrier function, and soothes redness, especially in sensitive, allergic, or polluted skin. Clinically proven effective for atopic dermatitis and rosacea.
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Evermat™
Evermat™ is a branded raw material that combines bark extract of the West African Enantia chlorantha tree with oleanolic acid. This combination of active ingredients addresses key mechanisms of oily skin: sebocyte activity, inflammation, and pore enlargement.
Oleanolic acid inhibits 5-alpha reductase, which reduces sebum production, while the plant extract has anti-inflammatory properties and reduces the expression of pore-enlarging markers such as keratin 16. Studies show visible pore reduction, decreased sebum production, and a more matte complexion after 28 days. Ideal for blemished, large-pored, or hormonally induced problem skin.
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Folic Acid
Folic acid (vitamin B9) is a water-soluble vitamin essential for DNA synthesis, cell division, and repair processes. In topical form, it stimulates the proliferation of epidermal cells and strengthens the skin structure at the molecular level.
Folic acid protects fibroblasts and keratinocytes from UV-induced DNA damage and contributes to the restoration of weakened skin functions. Studies show it promotes cell regeneration, improves skin elasticity, and strengthens the epidermal barrier. It is particularly suitable for use in anti-aging formulations, after dermatological treatments, or for stressed skin.
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Galactoarabinan
Galactoarabinan is a highly branched polysaccharide obtained from larch trees (mostly Larix occidentalis). It consists of galactose and arabinose units and is used in cosmetic formulations as a film-forming and moisturizing agent.
It forms a light, non-occlusive protective film on the skin, reduces water loss, and can support exfoliation by accelerating the skin's natural desquamation process. Furthermore, it improves the penetration of other active ingredients and is suitable as a carrier for moisturizing and smoothing products.
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Glycerin
Glycerin (glycerol) is a trihydric sugar alcohol that occurs naturally in lipid metabolism. In cosmetic products, it serves as a classic humectant, binding water from deeper skin layers or the surrounding environment.
It improves the hydration of the stratum corneum, softens the skin, and reduces irritation. Glycerin also supports epidermal lipid synthesis and stabilizes the skin barrier. Due to its excellent tolerability, it is universally applicable, from sensitive to dry skin.
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Glycine Soja Oil
Soybean oil is extracted from the seeds of the soybean (Glycine soja) and contains essential fatty acids, especially linoleic acid (omega-6), as well as phytosterols, lecithin, and vitamin E. It is one of the easily absorbed plant oils with high skin compatibility.
Linoleic acid supports the synthesis of ceramides and the stabilization of the skin barrier, while tocopherols have an antioxidant effect. Soybean oil has a soothing effect, promotes skin elasticity, and is particularly suitable for dry, sensitive, or inflamed skin conditions. It is also used as a carrier for lipophilic active ingredients.
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Witch hazel extract
Witch hazel extract is obtained from the leaves or bark of the North American witch hazel shrub (Hamamelis virginiana). Its main active ingredients are tannins (especially hamamelitannin), flavonoids, and essential oils. Witch hazel has astringent, anti-inflammatory, and mildly antimicrobial properties.
The tannins contained in witch hazel cause temporary constriction of superficial blood vessels and seal the capillary walls, thus reducing redness. Flavonoids neutralize free radicals and stabilize the skin barrier. Due to these properties, witch hazel is used particularly in toning and soothing formulations, for example, for sensitive, irritated, or blemished skin.
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Jojoba oil
Jojoba oil is a liquid wax extracted from the seeds of Simmondsia chinensis. Chemically, it consists primarily of wax esters, which are very similar to the composition of human sebum. This allows it to be absorbed easily without leaving a greasy residue.
It is non-comedogenic, anti-inflammatory, and antioxidant, supports the skin barrier, and regulates sebum production. The vitamin E it contains protects against oxidative stress. Especially suitable for dry, sensitive, blemished, or mature skin.
Chamomile flower extract
Chamomile flower extract is obtained from the flowers of Matricaria recutita (German chamomile) and contains pharmacologically relevant active ingredients such as bisabolol, chamazulene, flavonoids (apigenin), coumarins, and mucilage. The extract components have anti-inflammatory, antibacterial, antioxidant, and itch-relieving properties.
In particular, α-Bisabolol inhibits the cyclooxygenase and lipoxygenase pathways, thus reducing the formation of pro-inflammatory mediators. Chamazulene exhibits a free radical-binding effect, while apigenin contributes a mild anti-allergic component. Due to its versatile effects, chamomile extract is used especially for sensitive, irritated, reddened, or inflamed skin, also as a supportive treatment for atopic dermatitis or after dermatological procedures.
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Kigelia Africana Fruit Extract
The fruit extract of the Kigelia tree (Kigelia africana) is traditionally used in African medicine and contains flavonoids, iridoids, saponins, and phytosterols. These active ingredients have antioxidant, antimicrobial, and skin-firming effects.
Studies suggest that Kigelia extract improves skin elasticity, inhibits collagen breakdown, and has anti-inflammatory properties, especially in hormonally influenced or mature skin. It is also used to reduce pigmentation disorders and for oily, blemished skin. Its toning effect makes it attractive for firming skincare regimens.
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Lipochroman™
Dimethylmethoxy chromanol is a synthetic antioxidant from the chromanol group, structurally related to vitamin E. The branded raw material Lipochroman™ is particularly effective against reactive oxygen species (ROS) and nitrogen species (RNS) generated by UV radiation, pollution, and blue light.
Compared to classic antioxidants, lipochromate exhibits an exceptionally broad protective effect against oxidative cell damage, lipid peroxidation, and DNA damage. Studies demonstrate a reduction in oxidative markers as well as protection against inflammatory cascades that contribute to premature skin aging. Ideal in formulations for urban, light-induced, and digitally stressed skin ("urban aging," "digital aging").
Liposome
Lecithin is a phospholipid-rich complex derived from soy or egg yolk, structurally similar to cell membranes. In cosmetics, lecithin is frequently used to form liposomes, tiny vesicles that encapsulate active ingredients and deliver them directly to the skin.
The lipid components promote the skin's barrier function, improve the penetration of fat- and water-soluble active ingredients, and have a smoothing and nourishing effect on the skin. Lecithin is particularly suitable for sensitive, compromised, or mature skin and supports regeneration in cases of dryness or irritation.
almond oil
Almond oil is extracted from the ripe seeds of the sweet almond (Prunus amygdalus dulcis). It mainly contains oleic acid (omega-9), linoleic acid (omega-6), vitamin E, and phytosterols.
The fatty acid composition of almond oil makes it an ideal moisturizing skincare oil. It has a calming and soothing effect and supports the regeneration of the skin barrier. The high content of unsaturated fatty acids improves skin elasticity and reduces transepidermal water loss. Almond oil is particularly well-tolerated and is frequently used for sensitive, irritated, or dry skin.
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Matrixyl™ 3000
Matrixyl™ 3000 is a synergistic peptide complex consisting of:
Palmitoyl Tripeptide-1, which activates collagen and glycosaminoglycan synthesis,
Palmitoyl Tetrapeptide-7, which has anti-inflammatory properties.
The complex mimics the action of damaged collagen fragments (matrikines), resulting in accelerated repair of the extracellular matrix. Studies demonstrate a significant improvement in skin elasticity and a reduction in wrinkles after 2–3 months of regular use. Matrixyl™ 3000 is considered one of the most clinically studied anti-aging peptide complexes.
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Matrixyl OS 3000
Matrixyl™ 3000 OS is a biomimetic peptide complex consisting of two signaling peptides:
Palmitoyl Tripeptide-1 stimulates collagen and glycosaminoglycan synthesis,
Palmitoyl Tetrapeptide-7 reduces inflammatory markers such as IL-6.
The combination works synergistically: it strengthens the dermal matrix, promotes skin density, and reduces wrinkles. Studies demonstrate an improvement in skin structure and a significant anti-wrinkle effect after continuous use. Matrixyl™ is an established anti-aging active ingredient based on peptide technology, well-tolerated, and suitable for mature and sensitive skin.
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Melostem™
Melostem™ is a biotechnologically derived plant stem cell extract from Monarda didyma (bee balm). It contains secondary plant compounds such as flavonoids, rosmarinic acid, and antioxidant enzymes that have cell-protective and anti-inflammatory effects.
As an active ingredient derived from plant tissue culture, Melostem™ is characterized by high purity and controllable active ingredient profiles. It supports the skin in cases of oxidative stress (e.g., from UV radiation or environmental pollution), promotes mitochondrial function, and can stabilize the microbiome. Ideal for sensitive, reactive, or prematurely aging skin.
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Lactic acid
Lactic acid is an alpha hydroxy acid (AHA) that occurs naturally in human metabolism and in fermented foods. In skincare, it has keratolytic, moisturizing, and mild pH-regulating properties.
Lactic acid breaks down the bonds between dead skin cells (desmosomes), promoting cell renewal and refining skin texture. Simultaneously, it acts as a humectant, binding water in the skin. At higher concentrations (>5%), it has a more intensive exfoliating effect, while at lower concentrations (<2%) it is more hydrating. Lactic acid supports the skin barrier, regulates pH, and is also suitable for sensitive skin types.
Neurolight™
Sea daffodil extract (Pancratium maritimum) is the main ingredient in the branded raw material Neurolight™. It inhibits tyrosinase activity stimulated by neurogenic stimuli, which plays a central role in hyperpigmentation.
Neurolight intervenes early in the pigmentation process, particularly where stress, inflammation, or UV light activates melanocytes. Studies demonstrate a significant lightening of dark spots and a visible homogenization of skin tone without depigmenting intact skin areas. Ideal for sensitive, unevenly pigmented, or sun-damaged skin.
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Niacinamide
Niacinamide is the amidated form of the water-soluble vitamin B3 and plays a key role in numerous enzymatic reactions, particularly in energy production (NAD/NADP). When applied topically, it has a multifunctional effect: antioxidant, barrier-enhancing, sebum-regulating, pigment-balancing, and anti-inflammatory.
It increases the production of ceramides and free fatty acids in the skin, which improves barrier function and moisture retention. At the same time, it inhibits the transfer of melanosomes into keratinocytes, leading to a lightening of hyperpigmentation. Studies show that niacinamide is also effective in treating rosacea, acne, UV-induced skin aging, and atopic dermatitis, depending on the concentration and formulation.
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Oligohyaluron
Oligohyaluron, also known as hydrolyzed sodium hyaluronate, is an enzymatically or chemically fragmented hyaluronic acid with a very low molecular weight (< 10 kDa). Compared to high-molecular-weight hyaluronic acid, it can penetrate deeper into the epidermis.
There, it not only promotes moisture retention and reduces transepidermal water loss, but also stimulates the expression of skin barrier proteins such as filaggrin and the synthesis of the body's own hyaluronic acid. Its application demonstrably improves skin elasticity and volume, and smooths fine lines, making it particularly suitable for dry, mature, or stressed skin.
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Panthenol
Dexpanthenol is the biologically active alcohol form of pantothenic acid (vitamin B5) and a widely used active ingredient in medical and cosmetic skincare. After absorption in the skin, panthenol is enzymatically converted to coenzyme A, a key cofactor in cellular metabolism.
Panthenol has moisturizing, anti-inflammatory, and regenerative properties. It promotes keratinocyte proliferation, accelerates epithelialization, and improves the skin's barrier function by increasing lipid synthesis. It reduces transepidermal water loss (TEWL) and is particularly suitable for irritated, dry, cracked, or injured skin – including in the aftercare following dermatological procedures.
PDRN
Sodium DNA is a naturally occurring polymer of purified deoxyribonucleotides, usually derived from salmon or trout milt. As a medical agent, it is known as PDRN (polydeoxyribonucleotides) and is used in aesthetic medicine and dermatology for tissue regeneration.
PDRN binds to adenosine A2A receptors, activates growth factors (e.g., VEGF), and promotes fibroblast proliferation as well as DNA repair mechanisms. In cosmetics, sodium DNA exhibits repairing, cell-activating, and anti-inflammatory effects, which are particularly beneficial for sun-damaged, thin, or post-procedurally stressed skin.
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Pentavitin
Pentavitin™ is a biotechnologically produced sugar isomerate complex, structurally related to the carbohydrates of the natural skin barrier (stratum corneum). It binds specifically to the free amino groups of keratin and therefore remains in the skin even after washing.
Unlike conventional humectants, Pentavitin not only works on the surface but also provides deep hydration. It improves skin elasticity, reduces flaking and tightness, and strengthens the skin's barrier function. It is particularly suitable for dry, sensitive, and compromised skin.
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Saccharide Isomerated
Saccharide isomerate is a plant-based, biotechnologically produced sugar derivative that mimics the skin's natural moisturizing factors (NMF). It adheres firmly to keratin, creating an intense, long-lasting hydration effect, even after washing.
Studies have shown a significant reduction in transepidermal water loss, improved skin elasticity, and relief from dryness, flaking, or skin irritation. The active ingredient is non-occlusive and suitable for all skin types, including those prone to eczema or atopic dermatitis.
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Pullulan
Pullulan is a natural polysaccharide obtained through the fermentation of Aureobasidium pullulans. It consists of maltotriose units and, when applied topically, forms a flexible, firming film on the skin.
This film creates an immediately visible lifting effect, protects against environmental influences, and reduces transepidermal water loss. Furthermore, pullulan improves skin structure in the short term and can optimize the absorption of other active ingredients. It is biodegradable, non-irritating, and frequently used in anti-aging and firming formulations.
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Renovage™
Renovage™ is a patented, branded raw material based on teprenone, a derivative of the geranylgerane group. Its mechanism of action is based on the stabilization of telomeres and the extension of cellular lifespan. It is a so-called cell-protecting agent that is intended to slow down aging processes at the molecular level.
Studies show that Renovage improves skin texture, reduces pore size, redness, and pigmentation irregularities, and increases skin hydration. At the same time, it reduces cellular stress reactions, resulting in a smoother, more vibrant complexion. The active ingredient is particularly suitable for use in anti-aging formulations and for treating stress-related skin aging.
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Resveratrol
Resveratrol is a natural polyphenol found, among other places, in the skin of grapes. It is known for its strong antioxidant properties and its ability to modulate cellular stress responses.
In the skin, resveratrol inhibits free radicals, activates sirtuins (especially SIRT1), so-called longevity enzymes, and regulates inflammatory processes. It counteracts photoaging, promotes collagen stability, and protects DNA and mitochondria from damage. Its use is particularly beneficial in anti-aging, repair, and antioxidant skincare concepts.
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Retinatural™
Retinaturel™ is a branded raw material that combines plant-based retinoid alternatives, such as bakuchiol (from Psoralea corylifolia) or retinol-like molecules from algae extracts or herbs. It targets similar mechanisms of action to retinol, without its irritating properties.
Retinaturel activates the gene expression of retinoid-like signaling pathways (RAR/RXR-independent), stimulates collagen synthesis, improves skin texture, and has an antioxidant effect. Studies show comparable efficacy with improved skin tolerance compared to classic retinol. Retinaturel is used particularly in anti-aging formulations for sensitive or reactive skin.
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Salicylic Acid
Salicylic acid is a β-hydroxy acid (BHA) with keratolytic, comedolytic, and antimicrobial properties. It originally comes from willow bark but is now produced synthetically. Due to its lipophilic structure, it can penetrate deep into the pores and dissolve sebum and dead skin cells.
It works by weakening intercellular connections (desmosomes), thereby facilitating the shedding of dead skin cells. Salicylic acid also exhibits a mild anti-inflammatory effect through COX inhibition. It is clinically effective in concentrations from 0.5% (acne care) to 2% (cosmetic) and up to 30% (medicinal peel). It is particularly effective for oily, blemished skin and for preventing blackheads.
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Sheabutter
Sheabutter is extracted from the nuts of the shea tree (Vitellaria paradoxa) and consists of a mixture of triglycerides, waxes, unsaponifiable components (primarily triterpenes and tocopherols), and phytosterols. These natural lipids have occlusive, anti-inflammatory, and regenerative properties.
Sheabutter strengthens the skin barrier, reduces transepidermal water loss, and supports wound healing. Antioxidants such as vitamin E protect cells from oxidative stress, while triterpenes (e.g., lupeol) have anti-inflammatory properties. Shea butter is excellent for the care of dry, irritated, or barrier-impaired skin, including skin with atopic dermatitis, and can be used as a base for moisturizing creams
Sodium Lactate
Sodium lactate is the sodium salt of lactic acid and a component of the skin's natural moisturizing factor (NMF). It acts as a humectant, meaning it attracts water and retains it in the upper layer of the skin.
It improves skin hydration, increases suppleness, and supports skin elasticity. As a mild pH-regulating substance, it is frequently used in combination with other NMF components and is particularly suitable for dry, sensitive, and dehydrated skin.
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Sodium PCA / PCA
Sodium PCA is the sodium salt of pyrrolidone carboxylic acid, a naturally occurring component of the NMF in the stratum corneum. It has a very high water-binding capacity and therefore acts as a strong hydrator without being occlusive.
It stabilizes the skin barrier, making the skin smoother and more resistant to external influences. Due to its excellent tolerability, Sodium PCA is suitable for all skin types, especially dry, flaky, and sensitive skin.
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Sunflower oil
Sunflower oil is extracted from the seeds of the sunflower (Helianthus annuus) and consists mainly of unsaturated fatty acids, especially linoleic acid (omega-6), oleic acid, and tocopherols (vitamin E). It is one of the so-called "non-comedogenic" vegetable oils.
Linoleic acid is essential for the formation of ceramides and thus for the integrity of the skin barrier. Sunflower oil promotes the skin barrier, has antioxidant and anti-inflammatory properties – especially beneficial for irritated, dry, or atopic skin. Studies show that it can lower skin permeability and significantly reduce transepidermal water loss. Due to its good tolerability, it is also suitable for sensitive skin.
Syn®-Ake
Syn®-Ake is a synthetic tripeptide modeled after the Waglerin-1 peptide from the venom of the temple viper (Tropidolaemus wagleri). It acts as a competitive antagonist at muscle receptors and inhibits neuromuscular signal transmission.
By reversibly blocking acetylcholine receptors, Syn-Ake weakens facial muscle contractions – particularly in the forehead, eye, and lip areas. Studies show that topical Syn-Ake can visibly smooth wrinkles, especially with continuous use over 28 days. It is suitable as a gentle alternative or complement to injectable muscle relaxants.
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Tranexamic acid
Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine and works in dermatology primarily by inhibiting inflammation-induced melanin production. It blocks the plasminogen-plasmin pathway, which plays a central role in the activation of inflammatory mediators. This reduces the release of arachidonic acid and prostaglandins, which are signals that stimulate melanocytes to produce melanin.
In skincare, TXA has been shown to be effective in treating various forms of hyperpigmentation, including melasma, post-inflammatory hyperpigmentation (PIH), and UV-induced pigmentary disorders. Additionally, tranexamic acid supports the skin barrier, reduces redness, and mitigates the inflammatory cascade triggered by UV exposure and environmental stressors.
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Grape seed oil
Grape seed oil is obtained by cold pressing the seeds of the grape (Vitis vinifera). It contains a high proportion of linoleic acid (omega-6), vitamin E (especially tocopherol), and oligomeric proanthocyanidins (OPCs).
These ingredients have antioxidant and anti-inflammatory properties and strengthen the skin barrier. Linoleic acid supports ceramide production and improves skin permeability and hydration. OPCs bind free radicals and protect the collagen structure from enzymatic degradation. The oil is light, absorbs well, and is particularly suitable for sensitive, oily, or combination skin.
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Unisooth™
Unisooth™ is a patented anti-inflammatory compound made from polyphenolic antioxidants. The gallate derivatives it contains, particularly from green tea (EGCG) and plant origin (e.g., gallic acid), inhibit the activation of pro-inflammatory signaling pathways such as NF-κB and reduce the expression of inflammatory markers such as IL-1β and TNF-α.
Unisooth's effects are both antioxidant and immunomodulating, making it ideal for sensitive, irritated, or environmentally stressed skin. It also protects against skin irritation caused by UV or mechanical factors.
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Vitamin A palmitate
Retinyl palmitate is a fat-soluble ester of retinol (vitamin A) and palmitic acid. It is considered a mild form of retinol because it is enzymatically converted into active retinol in the skin. It is one of the most frequently used cosmetic retinoids.
Retinyl palmitate supports the proliferation of keratinocytes, stimulates collagen synthesis, and reduces wrinkle depth. It also has antioxidant properties and regulates skin keratinization. Although less potent than retinol, its high tolerability makes it particularly suitable for sensitive skin.
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Vitamin E
Vitamin E (mostly in the form of α-tocopherol) is a fat-soluble antioxidant found in plant oils. In skincare, it is used to neutralize free radicals, especially those generated by UV radiation.
Tocopherol stabilizes cell membranes, reduces lipid peroxidation, and supports skin regeneration after oxidative stress. It also has anti-inflammatory properties, promotes wound healing, and strengthens the skin barrier function by improving the lipid structure in the stratum corneum. In combination with vitamin C, it exerts synergistic antioxidant effects.
Wild Yam Extract
Wild yam is a plant extract from the root of Dioscorea villosa and contains diosgenin – a steroid-like saponin that can be used as a precursor for the synthesis of progesterone and other steroid hormones (in the pharmaceutical industry, not directly in the skin).
In cosmetics, wild yam is primarily used in connection with hormonally induced skin changes (e.g., during perimenopause). It exhibits antioxidant and anti-inflammatory properties, supports skin regeneration, and promotes collagen synthesis. Its effect on hormonal skin processes is controversial, but the plant extract is considered soothing, barrier-strengthening, and nourishing – especially for mature or dry skin.
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