Pentavitin® (INCI: Saccharide Isomerate) is a 100% natural active ingredient of plant origin. Chemically, it is a sugar complex, similar to the natural carbohydrates found in human skin. This structure allows Pentavitin® to bind specifically to the outermost layer of skin, the stratum corneum, and retain long-lasting moisture there. This effect lasts up to 72 hours, even after repeated washing, as studies have shown. Furthermore, Pentavitin® supports the formation of important barrier proteins such as filaggrin, thus improving the skin's resistance to environmental stressors. In studies, the skin appeared visibly smoother and healthier.

The hydrating effect is accompanied by a strengthening of the skin barrier: Pentavitin promotes the formation of skin-stabilizing proteins such as filaggrin, thus supporting resistance to environmental influences. Initial studies also suggest a soothing effect on dry or irritated skin.

This combination has been proven to strengthen the barrier function, increase water retention in the epidermis and protect against transepidermal water loss, even in the sensitive eye area.

This is a modified form of the well-known hyaluronic acid, in which some hydroxyl groups are replaced by acetyl groups. This structural change increases the molecule's lipophilicity (making it more fat-soluble), thereby improving its absorption into the skin and simultaneously making it more stable against enzymatic degradation by hyaluronidases. The result is deep and long-lasting hydration. The acetyl groups act as molecular anchors, binding water in the uppermost layer of skin particularly efficiently over a longer period and are more stable than conventional hyaluronic acid.

In a clinical study, sodium acetylated hyaluronate demonstrated a significant 9% reduction in nasolabial folds after 6 hours and a reduction of approximately 6% in fine crow's feet compared to placebo. These effects were maintained with continuous use over several weeks. Molecular analyses also show that the acetylated form inhibits UV- and environmentally induced activity of matrix metalloproteinases (MMPs), enzymes that accelerate the degradation of collagen and elastin. This specifically protects the structure of the extracellular matrix (ECM). The improved enzyme resistance and increased skin affinity allow for more effective utilization of hyaluronic acid, even in deeper skin layers, with a measurably prolonged effect.

Two select plant oils for the eye area: Sweet almond oil (Prunus amygdalus dulcis), with its high content of monounsaturated and polyunsaturated fatty acids, strengthens the lipid matrix in the outermost layer of skin (stratum corneum), thus specifically supporting the barrier function. Grape seed oil (Vitis vinifera seed oil), rich in linoleic acid and antioxidant vitamin E, promotes skin elasticity and protects against oxidative stress, an effect that has been demonstrated in clinical pilot studies on epidermal regeneration, particularly in dry or irritated skin.

Result: The two plant oils stabilize the skin barrier, protect against external irritants and support an elastic, resilient skin appearance in the sensitive eye area.