Skin soothing & protection with a focus on inflammaging & dark circles

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This active complex combines Unisooth™ EG-28 with Biophytex™ to specifically regulate silent inflammation (“InflammAging”), microcirculation disorders and skin stress, with a special focus on the sensitive eye area.

Gallate complex of green tea, oak leaves & propyl gallate: Deep penetration with immediate effect

Unisooth™ EG-28 contains a combination of three highly active gallate derivatives:

Epigallocatechin gallatyl glucoside (EGCG-G) from green tea

Gallyl glucosides from oak leaves

Propyl gallate, known as a lipoxygenase inhibitor with strong antioxidant effects


These molecules not only have a long-term effect at the cellular level, but also noticeably soothe irritated skin within minutes. Studies show:

• -15% redness within 2 hours of irritation

-23% transepidermal water loss (TEWL measurement)

• Visible reduction of dark circles after 15 days (noticeable reduction of pigmentation, swelling & microcirculatory congestion)


The complex has a biological effect via:

1. Inhibition of the NF-κB signaling pathway → Reduction of IL-8 & CXCL1

2. Promotes lymphatic drainage (VEGFR3) → less edema around the eyes

3. Vasorelaxation (relaxation of blood vessels to improve microcirculation) through HO-1 activation (activation of the cell's own protective system, Heme Oxygenase 1, with antioxidant, anti-inflammatory and vasodilating effects) → better microcirculation, less blood congestion


This triple action makes gallates ideal active ingredients against the underlying causes of dark circles, sensitive skin and stress-related redness, even in younger skin types.

Plant-based composition for microcirculation and skin soothing.

Biophytex™

This active ingredient complex also specifically targets microcirculation, vascular strength, inflammation reduction, and the protection of sensitive skin, thus calming the skin. It combines extracted active ingredients from horse chestnut, ruscus, centella, calendula, licorice root, and yeast, rich in saponins and flavonoids that strengthen the skin structure, reduce redness, and visibly harmonize the complexion.

The finest blood capillaries in the skin are particularly susceptible to microstress, whether from UV radiation, environmental factors, hormonal changes, or lack of sleep. If these capillaries become permeable or fragile, blood components can leak out and accumulate in the tissues. The result: dark circles under the eyes, redness, rosacea (visibly dilated blood vessels, usually in the cheek and nose area, fine, permanently visible blood vessels on the face, typically in sensitive or irritated skin), or a dull, uneven complexion.

This plant-based composition has a targeted effect here:

  • Strengthens capillary walls → reduces “microbleeds” and visible blood vessels (also known as telangiectasia, depending on the severity)

  • Activates microcirculation → improves oxygen supply and lymphatic drainage

  • Soothes sensitive skin → relieves redness, tightness and irritation.

Clinical results:

  • -35% redness & -21% visible vessels after 2 weeks (in case of couperose)

  • -65% stinging and skin irritation (for sensitive, dry skin)

  • -65% darkness under the eyes (significantly brighter & more even complexion)

These effects make Biophytex™ the ideal duo with Unisooth™ EG-28: While Unisooth specifically inhibits inflammatory cytokine axes and stimulates lymph flow, Biophytex stabilizes structural vascular functions and supports the tolerance of reactive skin, especially in the sensitive eye and cheek area.

This combination is particularly recommended for those prone to redness, dark circles, sensitive or irritated skin, and for those who wish to promote microcirculation in the long term to maintain an even, fresh complexion. It is very often especially suitable for men's skin.

Conclusion

Biophytex™ is a versatile plant-based active ingredient complex that synergistically promotes microcirculation, vascular integrity and skin soothing, for visibly smoother, healthier skin and a significantly improved skin feel, even in sensitive skin conditions.

Mode of action:

Strengthens capillaries, soothes redness, reduces dark circles and micro-redness, especially in the area of ​​the cheeks and nose.

Clinical result:

Visibly regenerated skin appearance, even on sensitive skin.