Science Deep Dive

360º Day & Night Serum

About the product

The 06 360° Day & Night Serum is an intervention and prevention at the cellular level for noticeably more radiance, protection and regeneration during the day and at night.

In this deep dive, you'll learn how our selected bioactive ingredients work deep within the skin's structure at a molecular level. We'll show you what they do, why we chose them, and how they help keep your skin healthy, resilient, and radiant.

The 06 360º Day & Night Serum is a cosmeceutical. The term was coined in 1984 by Dr. Albert Kligman, a combination of cosmetics and pharmaceuticals, for skincare products that are applied externally like cosmetics but have pharmaceutical-like effects, with scientifically proven benefits and a very low risk profile.

  • For whom?

    For all skin types, especially when skin simultaneously needs moisture, soothing, evenness and anti-aging, or is prone to redness, dark circles and first lines.

  • For what?

    It supports the skin barrier and microcirculation, soothes irritated skin, provides moisture and activates structure-supporting processes – for a more even complexion day and night.

  • What will I see and when?

    Instantly smoother, more nourished skin. After a few days, reddened areas appear more harmonious; a calmer, fresher complexion. Over the following weeks, a finer texture, visibly less redness, and increased elasticity. Results may vary from person to person.

“360°” stands for a multidimensional principle of action, in all directions of skin biology, from hydration to collagen production.

So why this complex combination of active ingredients?

Our skin is exposed to numerous stressors around the clock: environmental stress, UV radiation, inflammatory processes, resulting in loss of elasticity, collagen loss, and aging. The O6 360° Day & Night Serum is the scientifically sound answer to these challenges: medically developed by us, inspired by cutting-edge skin research, expertly implemented, and clinically tested on over 1,000 people. A heartfelt thank you for the feedback. This multi-complex serum comprises 18 core technologies, the most important of which we would like to explain in detail below:

Dive Deep

Our active ingredient groups

RU21 Radiance Lift™ for building, smoothing and glow

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Skin soothing & protection with a focus on inflammaging & dark circles

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Key active ingredients for structure, pigment balance & protection against aging

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We have carefully selected and combined these ingredients based on the latest findings in dermatology, aesthetic medicine, and molecular biology. Each element fulfills its own scientifically proven function. Unisooth and Biophytex work together to effectively reduce redness, niacinamide and ectoin strengthen the skin barrier and provide hydration, and RU21 Radiance Lift promotes collagen regeneration and hyaluronic acid production for smoother, firmer skin.

Counteracting skin aging: Our developments are based on the idea of ​​biologically counteracting aging. The 06 360° Day & Night Serum works on several levels:

  1. Regeneration – stimulating repair processes at the cellular level

  2. Protection – inhibits inflammation and UV damage

  3. Structure – Stimulate collagen and hyaluronic acid synthesis

  4. Hydration – deep, long-lasting moisture supply

  5. Radiance – Reduce redness, refine skin texture

Conclusion

Noticeable high-end multi-complex active ingredient cosmetics
with scientific and clinical evidence

The 06 360° Day & Night Serum combines state-of-the-art biotechnological and botanical active ingredients in a formulation based on clinical experience. Every ingredient has its place, scientifically validated and dermatologically tested.

Literature & Transparency - Notes

Badilli U, Inal O. Current Approaches in
Cosmeceuticals: Peptides, Biotics and Marine Biopolymers. Polymers (Basel).
2025 Mar 18;17(6):798. doi: 10.3390/polym17060798. PMID: 40292641; PMCID: PMC11946782.


Lintner K, Gerstein F, Solish N. A serum containing vitamins C & E and a matrix-repair tripeptide reduces facial signs of aging as evidenced by Primos® analysis and frequently repeated auto-perception. J Cosmet Dermatol. 2020
Dec;19(12):3262-3269. doi: 10.1111/jocd.13770. Epub 2020 Oct 26. PMID: 33103342; PMCID: PMC7756752.


Gorouhi F, Maibach HI. Role of topical peptides in preventing or treating aged skin. Int J Cosmet Sci. 2009 Oct;31(5):327-45. doi: 10.1111/j.1468-2494.2009.00490.x. Epub 2009 Jun 30.
PMID: 19570099.


Linder J. Understanding
cosmeceutical peptides. H&PC Today - Household Personal Care Today.
2014;9:23‐26. [ Google Scholar ]


Gao Q, Xu C, Tan M, Wang Y, Liu Y, Wang Y, Fan Y, Tao X, Lu W, Huang Y,
Teng Y. Hydrogel-Based Therapies for Photoaging: Current Advances and Future Perspectives. J Cosmet Dermatol. 2025 Jun;24(6):e70295. doi:
10.1111/jocd.70295. PMID: 40515408; PMCID: PMC12166275.


Saturnino C, Sinicropi MS, Parisi OI, Iacopetta D, Popolo A, Marzocco S,
Autore G, Caruso A, Cappello AR, Longo P, Puoci F. Acetylated hyaluronic acid:
enhanced bioavailability and biological studies. Biomed Res Int. 2014;2014:921549. doi: 10.1155/2014/921549. Epub 2014
Jul 8. PMID: 25114930; PMCID: PMC4121155.


Yoon JY, Kwon HH, Min SU, Thiboutot DM, Suh DH. Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes. J Invest Dermatol. 2013 Feb;133(2):429-40. doi: 10.1038/jid.2012.292. Epub 2012 Oct 25. PMID: 23096708.


Alvarez GV, Kang BY, Richmond AM, Hoss E, Sulewski R, Minkis K,
Rozenberg SS, Antonovich D, Boucher A, Bernstein EF, Bertucci V, Chapas AM,
Cohen JL, Council ML, Dover JS, Geronemus R, Given KML, Goldbach HS, Goldman MP, Hooper D, Kaufman J, Munavalli G, Pacheco TR, Rossi AM, Wilson S, Alam M. Skincare ingredients recommended by cosmetic dermatologists: A Delphi consensus
study. J Am Acad Dermatol. 2025 Apr 14:S0190-9622(25)00612-7. doi:
10.1016/j.jaad.2025.04.021. Epub ahead of print. PMID: 40233838.


Mentioned branded active ingredients from:

Sederma GmbH, D-41334 Nettetal, Kaldenkirchen

DSM Nutritional Products, 4002 Basel, Switzerland

ADEKA EUROPE GMBH, 40212 Düsseldorf

BASF Beauty Creations, 92593 Levallois-Perret Cedex, France

CODIF TECHNOLOGIE NATURELLE, 35417 Saint-Malo cedex, FRANCE

LIPOTEC SA, 08850 Gavà · Barcelona, ​​Spain

Induchem AG, 8604 Volketswil, Switzerland

The active ingredient information on this page is for general information purposes and is based on current specialist literature as well as data from our raw material suppliers.

Our products are designed for cosmetic use and do not claim to have any therapeutic effect. Results may vary from person to person. Use is at your own risk.

Internal user observation studies compiled feedback from clinical and home use on over 1,000 applications. This survey was non-interventional, without a control group or medical assessment; the analysis is based primarily on self-reported data and product feedback. It is not comparable to clinical studies but provides practical insights into skin feel and tolerability.

If you have known intolerances or existing skin problems, seek dermatological advice before use.

Note regarding fragrances:
If present, we use selected fragrances that are strictly regulated in the EU in very low concentrations, below known irritation thresholds.


Additional information:

The information on the respective product packaging, including the INCI list, is authoritative.

For external use only. Avoid contact with eyes. Keep out of reach of children.

Discontinue use and seek medical advice if irritation occurs. Do not use on broken skin.


Legal information:

Third-party brand and product names are used for identification purposes and are the property of their respective owners.


As of November 2025
About the product