Refill - 04 Skin Renewal Overnight Mask

Regeneration, firming and glow while you sleep.

This exceptional O4 Skin Renewal Overnight Mask is scientifically based nighttime skin regeneration. While you sleep, it works with state-of-the-art bioactive ingredients to deeply renew your skin. Three advanced retinoid forms—retinal, retinyl palmitate, and Retinatural®—stimulate cell renewal, promote collagen synthesis, and visibly smooth fine lines without causing irritation.

The RU21 Radiance Lift™ complex with biomimetic peptide and biotechnological hyaluronic acid supports the extracellular matrix, strengthens the skin structure, and increases elasticity. Renovage® protects cell DNA, stabilizes telomeres, and extends cell lifespan—a true advancement in healthy aging research.

Soothing active ingredients such as bisabolol, allantoin, and Mel[o]stem™ reduce micro-inflammation (inflammaging), soothe redness, and promote a smooth, calm complexion. Simultaneously, Neurolight® and botanical flavonoids brighten the skin by visibly reducing dark spots and making the complexion appear more even.

Antioxidants such as coenzyme Q10, vitamin E and lipochroman™ protect skin cells from oxidative stress, while shea butter and jojoba oil strengthen the barrier and lock in moisture.
Dermatologically tested, very well tolerated.

Texture & Skin Feel
A rich, creamy mask for overnight use. Spreads evenly, absorbs well, and leaves no sticky residue. Leaves skin feeling soft, smooth, and nourished.

In the evening, after cleansing, apply a thin, even layer to the face and neck, avoiding the eye area. Leave on overnight without rinsing. Start with two to three applications per week, then, depending on tolerance, daily use is possible.

Layering and other instructions: Do not layer simultaneously with other retinoids or strong chemical peels such as AHA or BHA. Always use a suitable sunscreen the following day. A slight tingling sensation may occur initially. Do not use during pregnancy or while breastfeeding. Avoid contact with the eyes.